Krueppel-Like Factor 4 (KLF4) Antibody
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Catalogue No: abx031663
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
Research Articles on Krueppel-Like Factor 4 (KLF4)
| Target | Krueppel-Like Factor 4 (KLF4) |
| Research Area | Signal Transduction, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 20-53 amino acids from the N-terminal region of human KLF4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43474 (UniProt, ExPASy) |
| UniProt Entry Name | KLF4_HUMAN |
| Gene Symbol | KLF4 |
| GeneID | 9314 |
| OMIM | 602253 |
| NCBI Accession | NP_004226.3 |
| HGNC | 6348 |
| KEGG | hsa:9314 |
| Ensembl | ENSG00000136826 |
| String | 9606.ENSP00000363804 |
| Molecular Weight | Calculated MW: 54.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |