Kelch Like Family Member 1 (KLHL1) Antibody

The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8),.

Target	Kelch Like Family Member 1 (KLHL1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human KLHL1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NR64 (UniProt, ExPASy)
UniProt Secondary AC	A8K5X0, Q5VZ64, Q9H4X4, Q9NR65, Q9P238
UniProt Entry Name	KLHL1_HUMAN
Gene Symbol	KLHL1
GeneID	57626
OMIM	605332
HGNC	6352
Ensembl	ENSG00000150361
String	9606.ENSP00000367075
Molecular Weight	82 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kelch Like Family Member 1 (KLHL1)

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