Kelch-Like Protein 22 (KLHL22) Antibody

REQUEST MORE INFO
Catalogue No: abx011076
Price: US$420.50
(Size: 100 µl)

Click on the image to see the image legend

Available Options

* Size:

Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.

Target Kelch-Like Protein 22 (KLHL22)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IF/ICC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human KLHL22 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q53GT1 (UniProt, ExPASy)
UniProt Secondary AC A8K3Q4, A8MTV3, B7Z2G1, D3DX30, Q96B68, Q96KC6
UniProt Entry Name KLH22_HUMAN
Gene Symbol KLHL22
GeneID 84861
HGNC 25888
KEGG hsa:84861
Ensembl ENSG00000099910
String 9606.ENSP00000331682
Molecular Weight 72 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Kelch-Like Protein 22 (KLHL22)


Write a review