Prostate-Specific Antigen / PSA (KLK3) Antibody

Catalogue No: abx001669
Price: £120.00
(Size: 20 µl)
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KLK3 Antibody is a Rabbit Polyclonal antibody against KLK3. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Target Prostate-Specific Antigen / PSA (KLK3)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KLK3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07288 (UniProt, ExPASy)
UniProt Secondary AC C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4
UniProt Entry Name KLK3_HUMAN
Gene Symbol KLK3
GeneID 354
OMIM 176820
HGNC 6364
KEGG hsa:354
Ensembl ENSG00000142515
String 9606.ENSP00000314151
Molecular Weight Calculated MW: 7 kDa, 23 kDa, 25 kDa, 26 kDa, 28 kDa
Observed MW: 28 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Prostate-Specific Antigen / PSA (KLK3)

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