Kallikrein 5 (KLK5) Antibody

KLK5 Antibody is a Rabbit Polyclonal antibody against KLK5. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

Target	Kallikrein 5 (KLK5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 41-177 of human KLK5.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y337 (UniProt, ExPASy)
UniProt Secondary AC	A0A024R4G4, Q53ZR3, Q9HBG8
UniProt Entry Name	KLK5_HUMAN
Gene Symbol	KLK5
GeneID	25818
NCBI Accession	NP_036559.1
String	9606.ENSP00000337733
Molecular Weight	Calculated MW: 32 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kallikrein 5 (KLK5)

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