+44 (0) 1223 755950
+1 832 327 7413
Kallikrein 7 (KLK7) Antibody
REQUEST MORE INFO
Catalogue No: abx004221
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
Kallikrein 7 (KLK7) Antibody is a Rabbit Polyclonal antibody against Kallikrein 7 (KLK7). This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Research Articles on Kallikrein 7 (KLK7)
| Target | Kallikrein 7 (KLK7) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to KLK7. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49862 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K0U5, Q8N5N9, Q8NFV7 |
| UniProt Entry Name | KLK7_HUMAN |
| Gene Symbol | KLK7 |
| GeneID | 5650 |
| NCBI Accession | NP_644806.1 |
| KEGG | hsa:5650 |
| String | 9606.ENSP00000375683 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |