NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1) Antibody

KLRC1 Antibody is a Rabbit Polyclonal antibody against KLRC1. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

Target	NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P26715 (UniProt, ExPASy)
UniProt Entry Name	NKG2A_HUMAN
Gene Symbol	KLRC1
GeneID	3821
NCBI Accession	NP_015567.1
KEGG	hsa:3821
String	9606.ENSP00000438038
Molecular Weight	Calculated MW: 26 kDa Observed MW: 26 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1)

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