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NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1) Antibody
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Catalogue No: abx001145
Price:
US$348.00
(Size: 60 µl)
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KLRC1 Antibody is a Rabbit Polyclonal antibody against KLRC1. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Research Articles on NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1)
| Target | NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human KLRC1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P26715 (UniProt, ExPASy) |
| UniProt Entry Name | NKG2A_HUMAN |
| Gene Symbol | KLRC1 |
| GeneID | 3821 |
| NCBI Accession | NP_015567.1 |
| KEGG | hsa:3821 |
| String | 9606.ENSP00000438038 |
| Molecular Weight | Calculated MW: 24 kDa/26 kDa Observed MW: 26 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
