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Killer Cell Lectin Like Receptor C1 (KLRC1) Antibody

Catalogue No: abx001145
Price: £120.00
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KLRC1 Antibody is a Rabbit Polyclonal antibody against KLRC1. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

Target KLRC1
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KLRC1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P26715 (UniProt, ExPASy)
UniProt Entry Name NKG2A_HUMAN
Gene Symbol KLRC1
GeneID 3821
String 9606.ENSP00000438038
Molecular Weight Calculated MW: 24 kDa, 26 kDa
Observed MW: 26 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Killer Cell Lectin Like Receptor C1 (KLRC1) Antibody

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