Kininogen 1 (KNG1) Antibody

KNG1 Antibody is a Rabbit Polyclonal antibody against KNG1. Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein. 11926-1-AP was generated against N-terminal 300 aa of HMW kininogen. It can bind both HMW and LMW kiniogen.

Target	Kininogen 1 (KNG1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human Kininogen 1 (KNG1).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01042 (UniProt, ExPASy)
UniProt Secondary AC	A8K474, B2RCR2, C9JEX1, P01043, Q53EQ0, Q6PAU9, Q7M4P1
UniProt Entry Name	KNG1_HUMAN
Gene Symbol	KNG1
GeneID	3827
NCBI Accession	NP_000884.1
KEGG	hsa:3827
String	9606.ENSP00000265023
Molecular Weight	Calculated MW: 72 kDa Observed MW: 72 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kininogen 1 (KNG1)

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