Importin Subunit Alpha-2 (KPNA2) Antibody

Catalogue No: abx001367
Price: £120.00
(Size: 20 µl)
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Importin Subunit Alpha-2 (KPNA2) Antibody Importin Subunit Alpha-2 (KPNA2) Antibody

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KPNA2 Antibody is a Rabbit Polyclonal antibody against KPNA2. The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq, Jul 2008].

Target KPNA2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KPNA2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52292 (UniProt, ExPASy)
UniProt Secondary AC B9EJD6, Q53YE3, Q6NVW7, Q9BRU5
UniProt Entry Name IMA1_HUMAN
Gene Symbol KPNA2
GeneID 3838
KEGG hsa:3838
String 9606.ENSP00000438483
Molecular Weight Calculated MW: 57 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Importin Subunit Alpha-2 (KPNA2) Antibody

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