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GTPase KRas (KRAS) Antibody

Catalogue No: abx001104
Price: £120.00
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GTPase KRas (KRAS) Antibody GTPase KRas (KRAS) Antibody GTPase KRas (KRAS) Antibody GTPase KRas (KRAS) Antibody

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KRAS Antibody is a Rabbit Polyclonal antibody against KRAS. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Target KRAS
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KRAS.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01116 (UniProt, ExPASy)
UniProt Secondary AC A8K8Z5, B0LPF9, P01118, Q96D10
UniProt Entry Name RASK_HUMAN
Gene Symbol KRAS
GeneID 3845
KEGG hsa:3845
String 9606.ENSP00000256078
Molecular Weight Calculated MW: 21 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.28 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on GTPase KRas (KRAS) Antibody

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