GTPase KRas (KRAS) Antibody

KRAS Antibody is a Rabbit Polyclonal antibody against KRAS. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Target	GTPase KRas (KRAS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 30-189 of human KRAS.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01116 (UniProt, ExPASy)
UniProt Secondary AC	A8K8Z5, B0LPF9, P01118, Q96D10
UniProt Entry Name	RASK_HUMAN
Gene Symbol	KRAS
GeneID	3845
NCBI Accession	NP_203524.1
KEGG	hsa:3845
String	9606.ENSP00000256078
Molecular Weight	Calculated MW: 22 kDa Observed MW: 21 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	3.01 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on GTPase KRas (KRAS)

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