Keratin 81 (KRT81) Antibody

KRT81 Antibody is a Rabbit Polyclonal antibody against KRT81. The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Target	Keratin 81 (KRT81)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human KRT81.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14533 (UniProt, ExPASy)
UniProt Secondary AC	Q14846, Q16274, Q17R48, Q8WU52, Q9BR74
UniProt Entry Name	KRT81_HUMAN
Gene Symbol	KRT81
GeneID	3887
NCBI Accession	NP_002272.2
KEGG	hsa:3887
String	9606.ENSP00000369349
Molecular Weight	Calculated MW: 55 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Keratin 81 (KRT81)

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