KSHV ORF8 Antibody

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease.The genome of KSHV is 165-170 kb and contains at least 88 open reading frames.KSHV ORF8 is a virion envelope-associated protein.Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry.This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.

Target	KSHV ORF8
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
Isotype	IgG
Form	Liquid
Purification	Unpurified antiserum.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	4961501
Buffer	Rabbit anti-serum.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on KSHV ORF8

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