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Linker For Activation Of T-Cell (LAT) Antibody
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Catalogue No: abx004320
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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LAT Antibody is a Rabbit Polyclonal antibody against LAT. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Linker For Activation Of T-Cell (LAT)
| Target | Linker For Activation Of T-Cell (LAT) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human LAT |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43561 (UniProt, ExPASy) |
| UniProt Secondary AC | B7WPI0, C7C5T6, G5E9K3, O43919 |
| UniProt Entry Name | LAT_HUMAN |
| Gene Symbol | LAT |
| GeneID | 27040 |
| NCBI Accession | NP_055202.1 |
| KEGG | hsa:27040 |
| Molecular Weight | Calculated MW: 24 kDa/27 kDa/28 kDa Observed MW: 35 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
