Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK) Antibody
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Catalogue No: abx001789
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US$217.50
(Size: 20 µl)
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Datasheet SDS
LCK Antibody is a Rabbit Polyclonal antibody against LCK. This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Research Articles on Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK)
| Target | Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to LCK. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06239 (UniProt, ExPASy) |
| UniProt Entry Name | LCK_HUMAN |
| Gene Symbol | LCK |
| GeneID | 3932 |
| NCBI Accession | NP_005347.3 |
| KEGG | hsa:3932 |
| String | 9606.ENSP00000337825 |
| Molecular Weight | Calculated MW: 58 kDa Observed MW: 58 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |