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LCK (pY394) Antibody

Catalogue No: abx000234
Price: £220.00
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LCK (pY394) Antibody

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LCK (pY394) Antibody is a Rabbit Polyclonal antibody against LCK (pY394). This gene is a member of the Src family of protein tyrosine kinases (pYKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.

Target LCK (pY394)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y394 of human LCK.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P06239 (UniProt, ExPASy)
UniProt Entry Name LCK_HUMAN
Gene Symbol LCK
GeneID 3932
KEGG hsa:3932
String 9606.ENSP00000337825
Molecular Weight Calculated MW: 40 kDa, 58 kDa, 61 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on LCK (pY394) Antibody

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