Leptin (LEP) Antibody
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Catalogue No: abx004338
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US$304.50
(Size: 60 µl)
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Datasheet SDS
LEP Antibody is a Rabbit Polyclonal antibody against LEP. This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Research Articles on Leptin (LEP)
| Target | Leptin (LEP) |
| Research Area | Metabolism, Endocrinology, Cardiovascular Biology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Leptin |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P41159 (UniProt, ExPASy) |
| UniProt Secondary AC | O15158, Q56A88 |
| UniProt Entry Name | LEP_HUMAN |
| Gene Symbol | LEP |
| GeneID | 3952 |
| NCBI Accession | NP_000221.1 |
| KEGG | hsa:3952 |
| String | 9606.ENSP00000312652 |
| Buffer | PBS, pH 7.4, containing 1% protective protein, 0.02% sodium azide, 50% glycerol. |
| Concentration | 0.21 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
