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Leptin Receptor (LEPR) Antibody

Catalogue No: abx002178
Price: £120.00
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Leptin Receptor (LEPR) Antibody

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LEPR Antibody is a Rabbit Polyclonal antibody against LEPR. The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Target Leptin Receptor (LEPR)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human LEPR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48357 (UniProt, ExPASy)
UniProt Secondary AC Q13592, Q13593, Q13594, Q92919, Q92920, Q92921
Gene Symbol LEPR
GeneID 3953
KEGG hsa:3953
String 9606.ENSP00000330393
Molecular Weight Calculated MW: 96 kDa, 102 kDa, 103 kDa, 109 kDa, 132 kDa
Observed MW: 113 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Leptin Receptor (LEPR) Antibody

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