Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody
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Catalogue No: abx240161
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody is a Rabbit Polyclonal antibody for the detection of LILRB4. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4)
| Target | Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Leukocyte immunoglobulin-like receptor subfamily B member 4 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8NHJ6 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHL5 |
| UniProt Entry Name | LIRB4_HUMAN |
| KEGG | hsa:11006 |
| String | 9606.ENSP00000375616 |
| Molecular Weight | Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |