LGR5 (loop2) Antibody
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Catalogue No: abx031683
Price:
US$326.25
(Size: 50 µl)
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Datasheet SDS
LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
Research Articles on LGR5 (loop2)
| Target | LGR5 (loop2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/100, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 689-719 amino acids from human LGR5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75473 (UniProt, ExPASy) |
| UniProt Secondary AC | D8MCT0, Q4VAM0, Q4VAM2, Q9UP75 |
| UniProt Entry Name | LGR5_HUMAN |
| NCBI Accession | NP_001264155.1 NP_003658.1 |
| KEGG | hsa:8549 |
| String | 9606.ENSP00000266674 |
| Molecular Weight | Calculated MW: 100 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |