Human Lipoprotein Lipase (LPL) Protein
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Catalogue No: abx073909
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US$261.00
(Size: 2 µg)
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Datasheet SDS
Human Lipoprotein Lipase (LPL) Enzyme is a recombinant enzyme produced in HEK cells. LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008].
Research Articles on Lipoprotein Lipase (LPL)
| Target | Lipoprotein Lipase (LPL) |
| Research Area | Enzymes and Kinases, Metabolism, Cardiovascular Biology |
| Target Modification | Asn318Ser |
| Modification | Mutation |
| Origin | Human |
| Expression | Recombinant |
| Host | HEK293 cells |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Activity | Not tested |
| Purification | 0.4 µm filtered prior to lyophilization. Non-sterile. |
| Reconstitution | Reconstitute in deionized water to a concentration of 0.5 mg/ml. Filter using a sterile filter prior to use in cell culture. |
| Storage | Store lyophilized at -18°C for long term storage. It is recommended to add a carrier protein (0.1% HSA or BSA). Upon reconstitution, store at 4°C for up to 1 week. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06858 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5T9, Q16282, Q16283, Q96FC4 |
| UniProt Entry Name | LIPL_HUMAN |
| KEGG | hsa:4023 |
| String | 9606.ENSP00000309757 |
| Molecular Weight | 51.8 kDa |
| Sequence | HVDYKDDDDK PAGADQ RRDFIDIESK FALRTPEDTA EDTCHLIPGV AESVATCHFN HSSKTFMVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLSRAQEH YPVSAGYTKL VGQDVARFIN WMEEEFNYPL DNVHLLGYSL GAHAAGIAGS LTNKKVNRIT GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ PGCNIGEAIR VIAERGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CSSKEAFEKG LCLSCRKNRC NNLGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTESETHTNQ AFEISLYGTV AESENIPFTL PEVSTNKTYS FLIYTEVDIG ELLMLKLKWK SDSYFSWSDW WSSPGFAIQK IRVKAGETQK KVIFCSREKV SHLQKGKAPA VFVKCHDKSL NKKSG |
| Tag | N-terminal Flag tag |
| Buffer | Prior to lyophilization: 20 mM Tris, 50 mM NaCl, pH 7.5 |
| Concentration | Prior to lyophilization: 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |