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Lamin B1 (LMNB1) Antibody

Catalogue No: abx001562
Price: £160.00
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Lamin B1 (LMNB1) Antibody Lamin B1 (LMNB1) Antibody Lamin B1 (LMNB1) Antibody Lamin B1 (LMNB1) Antibody

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LMNB1 Antibody is a Rabbit Polyclonal antibody against LMNB1. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Target LMNB1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human LMNB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20700 (UniProt, ExPASy)
UniProt Secondary AC B2R6J6, Q3SYN7, Q96EI6
UniProt Entry Name LMNB1_HUMAN
Gene Symbol LMNB1
GeneID 4001
KEGG hsa:4001
String 9606.ENSP00000261366
Molecular Weight Calculated MW: 66 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Lamin B1 (LMNB1) Antibody

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