Low Density Lipoprotein Receptor (LDLR) Antibody

Low Density Lipoprotein Receptor (LDLR) Antibody is a Rabbit Polyclonal antibody for the detection of LDLR.

LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

Target	Low Density Lipoprotein Receptor (LDLR)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	low density lipoprotein receptor
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P01130 (UniProt, ExPASy)
UniProt Entry Name	LDLR_HUMAN
Gene Symbol	LDLR
GeneID	3949
OMIM	143890
HGNC	6547
KEGG	hsa:3949
Ensembl	ENSG00000130164
String	9606.ENSP00000454071
Molecular Weight	Observed MW: 100-160 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Low Density Lipoprotein Receptor (LDLR)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue