Lipoprotein A (LPA) Antibody

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I.The encoded protein constitutes a substantial portion of lipoprotein (a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis.Elevated plasma levels of this protein are linked to atherosclerosis.Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains.The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.

Target	Lipoprotein A (LPA)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human LPA (AA: 4330-4521) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08519 (UniProt, ExPASy)
UniProt Secondary AC	Q5VTD7, Q9UD88
UniProt Entry Name	APOA_HUMAN
Gene Symbol	LPA
GeneID	4018
OMIM	152200
HGNC	6667
Ensembl	ENSG00000198670
String	9606.ENSP00000321334
Molecular Weight	501 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lipoprotein A (LPA)

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