Lipoprotein Lipase (LPL) Antibody

LPL: lipoprotein lipase, also known as LIPD, HDLCQ11. Entrez Protein: NP000228. It is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

Target	Lipoprotein Lipase (LPL)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of LPL expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P06858 (UniProt, ExPASy)
UniProt Secondary AC	B2R5T9, Q16282, Q16283, Q96FC4
UniProt Entry Name	LIPL_HUMAN
Gene Symbol	LPL
GeneID	4023
OMIM	144250
HGNC	6677
KEGG	hsa:4023
Ensembl	ENSG00000175445
String	9606.ENSP00000309757
Molecular Weight	53.1 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lipoprotein Lipase (LPL)

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