Lysine-Specific Histone Demethylase 1A (LSD1) Antibody
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Catalogue No: abx011625
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Research Articles on Lysine-Specific Histone Demethylase 1A (LSD1)
| Target | Lysine-Specific Histone Demethylase 1A (LSD1) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Monkey |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human LSD1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O60341 (UniProt, ExPASy) |
| UniProt Entry Name | KDM1A_HUMAN |
| GeneID | 23028 |
| KEGG | hsa:23028 |
| String | 9606.ENSP00000383042 |
| Molecular Weight | 93 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |