Leucine Zipper Tumor Suppressor 2 (LZTS2) Antibody

Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.

Target	Leucine Zipper Tumor Suppressor 2 (LZTS2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 572-601 amino acids from the C-terminal region of human LZTS2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BRK4 (UniProt, ExPASy)
UniProt Secondary AC	B1AL14, D3DR72, Q8N3I0, Q96J79, Q96JL2
UniProt Entry Name	LZTS2_HUMAN
Gene Symbol	LZTS2
String	9606.ENSP00000359240
Molecular Weight	Calculated MW: 72.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Leucine Zipper Tumor Suppressor 2 (LZTS2)

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