Cholecystokinin Receptor Type A (M Cckar) Antibody

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

Target	Cholecystokinin Receptor Type A (M Cckar)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O08786 (UniProt, ExPASy)
UniProt Secondary AC	Q8VCC7, Q9DBV6
UniProt Entry Name	CCKAR_MOUSE
NCBI Accession	NP_033957.1
KEGG	mmu:12425
String	10090.ENSMUSP00000031093
Molecular Weight	Calculated MW: 48.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat Cckar.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cholecystokinin Receptor Type A (M Cckar)

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