Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1) Antibody

MAD1L1 Antibody is a Rabbit Polyclonal antibody against MAD1L1. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Target	Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MAD1/MAD1/MAD1L1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y6D9 (UniProt, ExPASy)
UniProt Secondary AC	B3KR41, Q13312, Q75MI0, Q86UM4, Q9UNH0
UniProt Entry Name	MD1L1_HUMAN
Gene Symbol	MAD1L1
GeneID	8379
NCBI Accession	NP_001013859.1
String	9606.ENSP00000385334
Molecular Weight	Calculated MW: 83 kDa Observed MW: 95 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitotic Spindle Assembly Checkpoint Protein MAD1 (MAD1L1)

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