Transcription Factor MafG (MAFG) Antibody

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).

Target	Transcription Factor MafG (MAFG)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAFG.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15525 (UniProt, ExPASy)
UniProt Entry Name	MAFG_HUMAN
Gene Symbol	MAFG
KEGG	hsa:4097
String	9606.ENSP00000350369
Molecular Weight	Calculated MW: 17.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Chicken MAFG.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transcription Factor MafG (MAFG)

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