Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Antibody
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Catalogue No: abx028819
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US$326.25
(Size: 80 µl)
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Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Research Articles on Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF)
| Target | Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) |
| Research Area | Tumor Immunity, Neuroscience, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human MANF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P55145 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14CX4, Q86U67, Q96IS4 |
| UniProt Entry Name | MANF_HUMAN |
| GeneID | 7873 |
| KEGG | hsa:7873 |
| String | 9606.ENSP00000432799 |
| Molecular Weight | Calculated MW: 20.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow MANF. |
| Concentration | 0.4 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |