MAP2K1 (phospho-pS221) Antibody

MAP2K1 (phospho-pS221) Antibody is a Rabbit Polyclonal antibody against MAP2K1 (phospho-pS221). The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Target	MAP2K1 (phospho-pS221)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around S221 of human MEK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q02750 (UniProt, ExPASy)
UniProt Entry Name	MP2K1_HUMAN
Gene Symbol	MAP2K1
GeneID	5604
NCBI Accession	NP_002746.1
KEGG	hsa:5604
String	9606.ENSP00000302486
Molecular Weight	Calculated MW: 43 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on MAP2K1 (phospho-pS221)

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