MAP2K3 (pS189) Antibody

Catalogue No: abx000143
Price: £120.00
(Size: 20 µl)
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MAP2K3 (pS189) Antibody is a Rabbit Polyclonal antibody against MAP2K3 (pS189). MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase. MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines. Activation of MKK3 and MKK6 occurs through phosphorylation of Ser189 and Thr193 on MKK3 and Ser207 and Thr211 on MKK6.

Target MAP2K3 (pS189)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S189 of human MAP2K3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46734 (UniProt, ExPASy) P52564 (UniProt, ExPASy)
UniProt Secondary AC B3KSK7, Q99441, Q9UE71, Q9UE72
UniProt Entry Name MP2K3_HUMAN
Gene Symbol MAP2K3, MAP2K6
GeneID 5606
String 9606.ENSP00000345083
Molecular Weight Calculated MW: 36 kDa, 39 kDa, 31 kDa, 37 kDa
Observed MW: Refer to Figures
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MAP2K3 (pS189)

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