Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibody
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Catalogue No: abx033755
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US$326.25
(Size: 80 µl)
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Datasheet SDS
MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.
Research Articles on Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5)
| Target | Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 127-156 amino acids from human MAP2K5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13163 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DE43, Q92961, Q92962 |
| UniProt Entry Name | MP2K5_HUMAN |
| KEGG | hsa:5607 |
| String | 9606.ENSP00000178640 |
| Molecular Weight | Calculated MW: 50.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |