Dual Specificity Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) Antibody

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase.MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals.This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.Tissue specificity: Isoform 2 is only expressed in skeletal muscle.Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.

Target	Dual Specificity Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human MAP2K6 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	5608
Molecular Weight	38 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dual Specificity Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6)

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