Dual Specificity Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibody

MAP2K7 Antibody is a Rabbit Polyclonal antibody against MAP2K7. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Target	Dual Specificity Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MEK7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14733 (UniProt, ExPASy)
UniProt Entry Name	MP2K7_HUMAN
Gene Symbol	MAP2K7
GeneID	5609
NCBI Accession	NP_660186.1
KEGG	hsa:5609
String	9606.ENSP00000381070
Molecular Weight	Calculated MW: 47 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dual Specificity Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7)

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