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Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody
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Catalogue No: abx029258
Price:
US$326.25
(Size: 80 µl)
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The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Research Articles on Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3)
| Target | Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAP3K7IP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8N5C8 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NDD9, Q6VQR0 |
| UniProt Entry Name | TAB3_HUMAN |
| Gene Symbol | TAB3 |
| KEGG | hsa:257397 |
| String | 9606.ENSP00000368215 |
| Molecular Weight | Calculated MW: 78.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse TAB3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |