Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Antibody
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Catalogue No: abx026743
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Research Articles on Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)
| Target | Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 321-349 amino acids from the Central region of human MAP4K2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q12851 (UniProt, ExPASy) |
| UniProt Secondary AC | Q86VU3 |
| UniProt Entry Name | M4K2_HUMAN |
| Gene Symbol | MAP4K2 |
| GeneID | 5871 |
| OMIM | 603166 |
| HGNC | 6864 |
| KEGG | hsa:5871 |
| Ensembl | ENSG00000168067 |
| String | 9606.ENSP00000294066 |
| Molecular Weight | Calculated MW: 91.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse MAP4K2. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |