Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody
REQUEST MORE INFO
Catalogue No: abx032957
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
Research Articles on Melanoma Antigen Preferentially Expressed In Tumors (PRAME)
| Target | Melanoma Antigen Preferentially Expressed In Tumors (PRAME) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P78395 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6Y7, O43481, Q8IXN8 |
| UniProt Entry Name | PRAME_HUMAN |
| Gene Symbol | PRAME |
| GeneID | 23532 |
| OMIM | 606021 |
| NCBI Accession | NP_006106.1 NP_996836.1 NP_996837.1 NP_996838.1 NP_996839.1 |
| HGNC | 9336 |
| KEGG | hsa:23532 |
| Ensembl | ENSG00000185686 |
| String | 9606.ENSP00000445675 |
| Molecular Weight | Calculated MW: 57.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |