Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) Antibody

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Target	Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/120 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human MAPK3 recombinant protein.
Isotype	IgG1 Kappa
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27361 (UniProt, ExPASy)
UniProt Secondary AC	A8CZ58, B0LPG3, Q8NHX1
UniProt Entry Name	MK03_HUMAN
KEGG	hsa:5595
String	9606.ENSP00000263025
Molecular Weight	Calculated MW: 43.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3)

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