Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) Antibody

MAPK3 Antibody is a Rabbit Polyclonal antibody against MAPK3. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Target	Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human ERK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27361 (UniProt, ExPASy)
UniProt Secondary AC	A8CZ58, B0LPG3, Q8NHX1
UniProt Entry Name	MK03_HUMAN
Gene Symbol	MAPK3
GeneID	5595
NCBI Accession	NP_002737.2
KEGG	hsa:5595
String	9606.ENSP00000263025
Molecular Weight	Calculated MW: 43 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3)

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