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Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody

Catalogue No: abx000671
Price: £95.00
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Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody

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MAPK8 Antibody is a Rabbit Polyclonal antibody against MAPK8. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Target Mitogen Activated Protein Kinase 8 (MAPK8/JNK1)
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human MAPK8.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 35 kDa, 44 kDa, 48 kDa
Observed MW: 50 kDa
Swiss Prot P45983
GeneID 5599
Gene Symbol MAPK8
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mitogen Activated Protein Kinase 8 / JNK1 (MAPK8) Antibody

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