Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) Antibody
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Catalogue No: abx001162
Price:
US$232.00
(Size: 20 µl)
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(![Western blot analysis of various lysates using [KO Validated] JNK2 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.](https://www.abbexa.com/image/cache/data/products/18B/abx001162_1-500x500.jpg "Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) Antibody")
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Datasheet SDS
MAPK9 Antibody is a Rabbit Polyclonal antibody against MAPK9. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Research Articles on Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9)
| Target | Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to MAPK9. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P45984 (UniProt, ExPASy) |
| UniProt Entry Name | MK09_HUMAN |
| Gene Symbol | MAPK9 |
| GeneID | 5601 |
| NCBI Accession | NP_002743.3 |
| KEGG | hsa:5601 |
| String | 9606.ENSP00000394560 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 54 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |