Mitogen Activated Protein Kinase Binding Protein 1 (MAPKBP1) Antibody

Catalogue No: abx002043
Price: £120.00
(Size: 20 µl)
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MAPKBP1 Antibody is a Rabbit Polyclonal antibody against MAPKBP1. MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Target MAPKBP1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human MAPKBP1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60336 (UniProt, ExPASy)
UniProt Secondary AC A6NM93, A8K8P9, Q14CB5, Q14CD8, Q49AJ8, Q5W9G9
UniProt Entry Name MABP1_HUMAN
Gene Symbol MAPKBP1
GeneID 23005
KEGG hsa:23005
String 9606.ENSP00000393099
Molecular Weight Calculated MW: 23 kDa, 109 kDa, 134 kDa, 149 kDa, 163 kDa
Observed MW: 165 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MAPKBP1

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