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Microtubule-Associated Protein Tau Phospho-Ser396 (MAPT pS396) Antibody
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Catalogue No: abx000215
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US$232.00
(Size: 20 µl)
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Datasheet SDS
Microtubule-Associated Protein Tau Phospho-Ser396 (MAPT pS396) Antibody is a Rabbit Monoclonal antibody against Microtubule-Associated Protein Tau Phospho-Ser396 (MAPT pS396). The MAPT gene encodes the Microtubule-Associated Protein Tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Research Articles on Microtubule-Associated Protein Tau Phospho-Ser396 (MAPT pS396)
| Target | Microtubule-Associated Protein Tau Phospho-Ser396 (MAPT pS396) |
| Research Area | Metabolic Pathways, Neuroscience, Developmental Science |
| Clonality | Monoclonal |
| Clone | N797 |
| Target Modification | Ser396 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around S396. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10636 (UniProt, ExPASy) |
| UniProt Secondary AC | P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96 |
| UniProt Entry Name | TAU_HUMAN |
| Gene Symbol | MAPT |
| GeneID | 4137 |
| OMIM | 157140 |
| NCBI Accession | NP_058519.3 |
| HGNC | 6893 |
| KEGG | hsa:4137 |
| Ensembl | ENSG00000186868 |
| String | 9606.ENSP00000340820 |
| Molecular Weight | Calculated MW: 79 kDa Observed MW: 50-80 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 0.05% BSA, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |