Microtubule-Associated Protein 4R Tau Phospho-Thr231 (MAPT pT231) Antibody
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Catalogue No: abx000448
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US$232.00
(Size: 20 µl)
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MAPT (pT231) Antibody is a Rabbit Polyclonal antibody against MAPT (pT231). This gene encodes the microtubule-associated protein 4R Tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Research Articles on Microtubule-Associated Protein 4R Tau Phospho-Thr231 (MAPT pT231)
| Target | Microtubule-Associated Protein 4R Tau Phospho-Thr231 (MAPT pT231) |
| Clonality | Polyclonal |
| Target Modification | Thr231 |
| Modification | Phosphorylation |
| Reactivity | Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding T231 of human Tau |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10636-8 (UniProt, ExPASy) |
| UniProt Secondary AC | P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96 |
| UniProt Entry Name | TAU_HUMAN |
| Gene Symbol | MAPT |
| GeneID | 4137 |
| OMIM | 157140 |
| HGNC | 6893 |
| KEGG | hsa:4137 |
| Ensembl | ENSG00000186868 |
| String | 9606.ENSP00000340820 |
| Molecular Weight | Calculated MW: 79 kDa Observed MW: 50-80 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |