+44 (0) 1223 755950
+1 832 327 7413
Megakaryocyte Associated Tyrosine Kinase (MATK) Antibody
REQUEST MORE INFO
Catalogue No: abx005098
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
MATK Antibody is a Rabbit Polyclonal antibody against MATK. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Research Articles on Megakaryocyte Associated Tyrosine Kinase (MATK)
| Target | Megakaryocyte Associated Tyrosine Kinase (MATK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MATK |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42679 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KNZ9, Q9NST8 |
| UniProt Entry Name | MATK_HUMAN |
| Gene Symbol | MATK |
| GeneID | 4145 |
| NCBI Accession | NP_647611.1 |
| KEGG | hsa:4145 |
| String | 9606.ENSP00000378485 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
