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Methyl-CpG Binding Domain Protein 3 (MBD3) Antibody

Catalogue No: abx001836
Price: £120.00
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Methyl-CpG Binding Domain Protein 3 (MBD3) Antibody

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MBD3 Antibody is a Rabbit Polyclonal antibody against MBD3. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.

Target MBD3
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MBD3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O95983 (UniProt, ExPASy)
UniProt Secondary AC A8K4B7, D6W5Z2, Q6PIL9, Q6PJZ9, Q86XF4
UniProt Entry Name MBD3_HUMAN
Gene Symbol MBD3
GeneID 53615
KEGG hsa:53615
String 9606.ENSP00000412302
Molecular Weight Calculated MW: 29 kDa, 32 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Methyl-CpG Binding Domain Protein 3 (MBD3) Antibody

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