Guanine Nucleotide Exchange Factor DBS (MCF2L) Antibody
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Catalogue No: abx030565
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Research Articles on Guanine Nucleotide Exchange Factor DBS (MCF2L)
| Target | Guanine Nucleotide Exchange Factor DBS (MCF2L) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1049-1075 amino acids from the C-terminal region of human MCF2L. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15068 (UniProt, ExPASy) |
| UniProt Entry Name | MCF2L_HUMAN |
| Gene Symbol | MCF2L |
| KEGG | hsa:23263 |
| String | 9606.ENSP00000440374 |
| Molecular Weight | Calculated MW: 128 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |