DNA Replication Licensing Factor MCM2 (MCM2) Antibody
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Catalogue No: abx015924
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication.The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex.This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Research Articles on DNA Replication Licensing Factor MCM2 (MCM2)
| Target | DNA Replication Licensing Factor MCM2 (MCM2) |
| Research Area | Developmental Science |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MCM2 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49736 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7 |
| UniProt Entry Name | MCM2_HUMAN |
| Gene Symbol | MCM2 |
| GeneID | 4171 |
| OMIM | 116945 |
| HGNC | 6944 |
| KEGG | hsa:4171 |
| Ensembl | ENSG00000073111 |
| String | 9606.ENSP00000265056 |
| Molecular Weight | 125 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |