DNA Replication Licensing Factor MCM2 (MCM2) Antibody

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Catalogue No: abx015924
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication.The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex.This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

Target DNA Replication Licensing Factor MCM2 (MCM2)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human MCM2 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49736 (UniProt, ExPASy)
UniProt Secondary AC Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7
UniProt Entry Name MCM2_HUMAN
Gene Symbol MCM2
GeneID 4171
OMIM 116945
HGNC 6944
KEGG hsa:4171
Ensembl ENSG00000073111
String 9606.ENSP00000265056
Molecular Weight 125 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Replication Licensing Factor MCM2 (MCM2)


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