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DNA Replication Licensing Factor MCM2 (MCM2) Antibody

Catalogue No: abx034344
Price: £225.00
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DNA Replication Licensing Factor MCM2 (MCM2) Antibody

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MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

Target MCM2
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 649-677 amino acids from the C-terminal region of human MCM2.
Isotype IgG
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49736 (UniProt, ExPASy)
UniProt Secondary AC Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7
UniProt Entry Name MCM2_HUMAN
KEGG hsa:417
String 9606.ENSP00000265056
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Replication Licensing Factor MCM2 (MCM2) Antibody

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